Knouse Lab

Massachusetts Institute of Technology

Genome-scale CRISPR screening in a single mouse liver

Keys, H.R. and Knouse, K.A.

Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential

Swartz, S.Z., McKay, L.S., Su, K.C., Bury, L. Padegeh, A., Knouse, K.A., and Cheeseman, I.M.

Chromosome segregation fidelity in epithelia requires tissue architecture

Knouse, K.A., Lopez, K.E., Bachofner, M., and Amon, A.

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease

Stevens, K.R., Scull, M.A., Ramanan, V., Fortin, C.L., Chaturvedi, R.R., Knouse, K.A., et al.

Chromosome mis-segregation generates cell-cycle-arrested cells with complex karyotypes that are eliminated by the immune system

Santaguida, S., Richardson, A., Iyer, D.R., M’Saad, O., Zasadil, L., Knouse, K.A., et al.

Aneuploidy in cancer: seq-ing answers to old questions

Knouse, K.A., Davoli, T., Elledge, S.J., and Amon, A.

Detection of copy number alterations using single cell sequencing

Knouse, K.A., Wu, J., and Hendricks, A.

Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo

Pfau, S.J., Silberman, R.E., Knouse, K.A., and Amon, A.

Assessment of megabase-scale somatic copy number variation using single-cell sequencing

Knouse, K.A., Wu, J., and Amon, A.

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

Knouse, K.A., Wu, J., Whittaker, C.A., and Amon, A.