Massachusetts Institute of Technology
Lab News
November 15, 2022
Our lab’s first paper in which we establish genome-wide CRISPR screening in the mouse liver is now published online at Cell Genomics! We are so excited about the power of this platform to enable high-throughput genetic dissection of diverse phenomena within a living mammal.
December 15, 2021
Kristin enjoyed talking to MIT News about how she fell in love with liver regeneration and how she hopes it can inspire new therapies for organ injury and cancer. Check out this behind-the-scenes footage of our new lab!
MIT News interview
MIT Biology video
August 23, 2021
We have moved! Kristin has joined the MIT Department of Biology as an Assistant Professor and our lab has relocated to the Koch Institute for Integrative Cancer Research at MIT! We are thrilled to be part of this interdisciplinary environment unified by a mission to advance our understanding and treatment of human disease.
February 1, 2021
We are thrilled to share our development of genome-wide CRISPR screening within a living mouse! Our approach is accessible to diverse phenotypes and we look forward to the many insights now achievable with high-throughput functional genomics in an organ!
bioRxiv preprint
January 18, 2021
Kristin shares her reflections on MD-PhD training, how it shaped her research career, and advice for early stages of independence in an interview with the Harvard Health Policy Review. Hopefully these insights can be helpful for aspiring scientists or physicians!
HHPR interview
December 18, 2020
In light of travel restrictions, we Zoomed across the worlds of whiskey and chocolate for the holidays!
December 9, 2020
Congratulations to Kristina Lopez for being recognized by Faces of Cell! Kristina's fearlessness and determination in developing new techniques have opened so many directions for our lab and we have such high expectations and excitement for her future!
June 12, 2020
A transatlantic toast to celebrate the lab's second birthday, Diana Gomes's and Kristina Lopez's fellowships...and that we're still smiling on Zoom calls!
June 3, 2020
An extremely well-deserved (and well-distanced) congratulations to Kristina Lopez for being named a NASEM Ford Fellow! We are so proud of all you've overcome and accomplished and grateful for the unique perspective and creative solutions you bring to our lab and the scientific community.
Whitehead Institute press release
March 30, 2019
We welcome new lab members with a trip to the crazy organisms exhibit at the Museum of Science. Allegiances and nascent side-projects split across the extremophiles, but these elephant seals have some pretty cool adaptations too!
November 28, 2018
We enjoyed sharing our liver goals with the Aeronaut Brewing crowd as part of Science by the Pint. A wonderful initiative for bringing science into the community!
October 2, 2018
We are honored and grateful to have the support of the NIH Early Independence Award as we launch our investigations of quiescence and its applications to regenerative medicine!
Whitehead Institute press release
September 2, 2018
We celebrate our first three months (and three people!) with some off-site liver regeneration
August 23, 2018
Our work revealing the importance of tissue architecture for chromosome segregation fidelity is now published online at Cell. A potential explanation for chromosome instability in cancer, a limitation of two-dimensional culture systems, and a major inspiration for our use of the liver as an in vivo system!
MIT press release
HHMI press release
June 4, 2018
The Knouse Lab opens at the Whitehead Institute for Biomedical Research!
Whitehead Institute blog post
