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Lab News

November 15, 2022

Our lab’s first paper in which we establish genome-wide CRISPR screening in the mouse liver is now published online at Cell Genomics! We are so excited about the power of this platform to enable high-throughput genetic dissection of diverse phenomena within a living mammal.


MIT press release

December 15, 2021

         Kristin enjoyed talking to MIT News about how she           fell in love with liver regeneration and how she                   hopes it can inspire new therapies for organ injury             and cancer. Check out this behind-the-scenes                     footage of our new lab!

         MIT News interview
         MIT Biology video

August 23, 2021

We have moved! Kristin has joined the MIT Department of Biology as an Assistant Professor and our lab has relocated to the Koch Institute for Integrative Cancer Research at MIT! We are thrilled to be part of this interdisciplinary environment unified by a mission to advance our understanding and treatment of human disease.

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February 1, 2021

We are thrilled to share our development of genome-wide CRISPR screening within a living mouse! Our approach is accessible to diverse phenotypes and we look forward to the many insights now achievable with high-throughput functional genomics in an organ!

bioRxiv preprint

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January 18, 2021

Kristin shares her reflections on MD-PhD training, how it shaped her research career, and advice for early stages of independence in an interview with the Harvard Health Policy Review. Hopefully these insights can be helpful for aspiring scientists or physicians!

HHPR interview

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December 18, 2020

In light of travel restrictions, we Zoomed across the worlds of whiskey and chocolate for the holidays!


December 9, 2020

Congratulations to Kristina Lopez for being recognized by Faces of Cell! Kristina's fearlessness and determination in developing new techniques have opened so many directions for our lab and we have such high expectations and excitement for her future!

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June 12, 2020

A transatlantic toast to celebrate the lab's second birthday, Diana Gomes's and Kristina Lopez's fellowships...and that we're still smiling on Zoom calls! 

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June 3, 2020

An extremely well-deserved (and well-distanced) congratulations to Kristina Lopez for being named a NASEM Ford Fellow! We are so proud of all you've overcome and accomplished and grateful for the unique perspective and creative solutions you bring to our lab and the scientific community.

Whitehead Institute press release

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March 30, 2019

We welcome new lab members with a trip to the crazy organisms exhibit at the Museum of Science. Allegiances and nascent side-projects split across the extremophiles, but these elephant seals have some pretty cool adaptations too!

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November 28, 2018

We enjoyed sharing our liver goals with the Aeronaut Brewing crowd as part of Science by the Pint. A wonderful initiative for bringing science into the community!

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October 2, 2018

We are honored and grateful to have the support of the NIH Early Independence Award as we launch our investigations of quiescence and its applications to regenerative medicine!

Whitehead Institute press release

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September 2, 2018

We celebrate our first three months (and three people!) with some off-site liver regeneration

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August 23, 2018


Our work revealing the importance of tissue architecture for chromosome segregation fidelity is now published online at Cell. A potential explanation for chromosome instability in cancer, a limitation of two-dimensional culture systems, and a major inspiration for our use of the liver as an in vivo system!

MIT press release

HHMI press release

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June 4, 2018

The Knouse Lab opens at the Whitehead Institute for Biomedical Research!

Whitehead Institute blog post

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